Can I Run / gemma 4 12B it / on AMD Instinct MI210

Can I Run gemma 4 12B it on a AMD Instinct MI210?

Yes

Runs at full precision (f32). Zero quality loss.

Model size
12.0B
GPU memory
64.0GB
Smallest quant
Q2_K
Best fit
f32

14 quantizations fit your 64.0GB

QuantMin VRAMRecommendedFile sizeHeadroom
f32BEST49.0 GB50.5 GB0.2 GB+15.0 GB
fp1625.0 GB26.5 GB0.9 GB+39.0 GB
Q8_013.8 GB15.3 GB0.5 GB+50.3 GB
Q6_K10.9 GB12.4 GB9.8 GB+53.1 GB
Q5_K_M9.5 GB11.0 GB8.4 GB+54.5 GB
Q5_K_S9.3 GB10.8 GB8.2 GB+54.7 GB
Q4_18.5 GB10.0 GB7.4 GB+55.5 GB
Q4_K_M8.3 GB9.8 GB7.1 GB+55.7 GB
Q4_K_S7.9 GB9.4 GB6.8 GB+56.1 GB
Q4_07.8 GB9.3 GB6.7 GB+56.3 GB
Q3_K_L6.3 GB7.8 GB6.7 GB+57.7 GB
Q3_K_M6.0 GB7.5 GB5.7 GB+58.0 GB
Q3_K_S5.6 GB7.1 GB5.1 GB+58.4 GB
Q2_K5.0 GB6.5 GB5.1 GB+59.0 GB

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Full model details
gemma 4 12B it

All quant variants, benchmark scores, and use-case tags.

Best models for this GPU
AMD Instinct MI210

Top-ranked open-source models that fit in 64.0GB.

FAQ

Can the AMD Instinct MI210 run gemma 4 12B it?

Yes. The AMD Instinct MI210's 64.0GB of VRAM is enough to run gemma 4 12B it at f32 quantization (49.0GB required).

What's the best quantization to use?

f32 is the highest-precision quantization that fits in your 64.0GB. It uses about 49.0GB of memory and 50.5GB recommended for comfortable inference.

What if I need more headroom for context length?

KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.