Can I Run / GPT-OSS 20B / on NVIDIA B100
Can I Run GPT-OSS 20B on a NVIDIA B100?
Yes
Runs at full precision (fp16). Zero quality loss.
Model size
21.5B
GPU memory
192GB
Smallest quant
Q2_K
Best fit
fp16
12 quantizations fit your 192GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| fp16BEST | 44.0 GB | 45.5 GB | 13.8 GB | +148.0 GB |
| Q8_0 | 23.8 GB | 25.3 GB | 12.1 GB | +168.2 GB |
| Q6_K | 18.7 GB | 20.2 GB | 12.0 GB | +173.3 GB |
| Q5_K_M | 16.3 GB | 17.8 GB | 11.7 GB | +175.7 GB |
| Q5_K_S | 15.8 GB | 17.3 GB | 11.7 GB | +176.2 GB |
| Q4_1 | 14.4 GB | 15.9 GB | 11.6 GB | +177.6 GB |
| Q4_K_M | 14.0 GB | 15.5 GB | 11.6 GB | +178.0 GB |
| Q4_K_S | 13.3 GB | 14.8 GB | 11.6 GB | +178.7 GB |
| Q4_0 | 13.1 GB | 14.6 GB | 11.5 GB | +178.9 GB |
| Q3_K_M | 10.0 GB | 11.5 GB | 11.5 GB | +182.0 GB |
| Q3_K_S | 9.3 GB | 10.8 GB | 11.5 GB | +182.7 GB |
| Q2_K | 8.1 GB | 9.6 GB | 11.5 GB | +183.9 GB |
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Full model details
GPT-OSS 20B →
All quant variants, benchmark scores, and use-case tags.
Best models for this GPU
NVIDIA B100 →
Top-ranked open-source models that fit in 192GB.
FAQ
Can the NVIDIA B100 run GPT-OSS 20B?
Yes. The NVIDIA B100's 192GB of VRAM is enough to run GPT-OSS 20B at fp16 quantization (44.0GB required).
What's the best quantization to use?
fp16 is the highest-precision quantization that fits in your 192GB. It uses about 44.0GB of memory and 45.5GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.