Can I Run Mistral Medium 3.5 128B on a AMD Ryzen AI Max+ 395 (128GB)?
Runs at Q5_K_M — good quality with reasonable headroom.
3 quantizations fit your 96.0GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| Q5_K_MBEST | 91.7 GB | 93.2 GB | 88.3 GB | +4.3 GB |
| Q4_K_M | 78.4 GB | 79.9 GB | 74.9 GB | +17.6 GB |
| Q2_K | 43.0 GB | 44.5 GB | 46.6 GB | +53.0 GB |
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FAQ
Can the AMD Ryzen AI Max+ 395 (128GB) run Mistral Medium 3.5 128B?
Yes. The AMD Ryzen AI Max+ 395 (128GB)'s 96.0GB of unified memory is enough to run Mistral Medium 3.5 128B at Q5_K_M quantization (91.7GB required).
What's the best quantization to use?
Q5_K_M is the highest-precision quantization that fits in your 96.0GB. It uses about 91.7GB of memory and 93.2GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.