Can I Run / Mistral Medium 3.5 128B / on NVIDIA H100 80GB

Can I Run Mistral Medium 3.5 128B on a NVIDIA H100 80GB?

Yes

Runs at Q4_K_M — good quality with reasonable headroom.

Model size
128B
GPU memory
80.0GB
Smallest quant
Q2_K
Best fit
Q4_K_M

2 quantizations fit your 80.0GB

QuantMin VRAMRecommendedFile sizeHeadroom
Q4_K_MBEST78.4 GB79.9 GB74.9 GB+1.6 GB
Q2_K43.0 GB44.5 GB46.6 GB+37.0 GB

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Full model details
Mistral Medium 3.5 128B

All quant variants, benchmark scores, and use-case tags.

Best models for this GPU
NVIDIA H100 80GB

Top-ranked open-source models that fit in 80.0GB.

FAQ

Can the NVIDIA H100 80GB run Mistral Medium 3.5 128B?

Yes. The NVIDIA H100 80GB's 80.0GB of VRAM is enough to run Mistral Medium 3.5 128B at Q4_K_M quantization (78.4GB required).

What's the best quantization to use?

Q4_K_M is the highest-precision quantization that fits in your 80.0GB. It uses about 78.4GB of memory and 79.9GB recommended for comfortable inference.

What if I need more headroom for context length?

KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.