Can I Run Mistral Medium 3.5 on a AMD Ryzen AI Max+ 395 (128GB)?
Runs at Q8_0 — near-lossless quality.
4 quantizations fit your 96.0GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| Q8_0BEST | 75.4 GB | 76.9 GB | 74.4 GB | +20.6 GB |
| Q6_K | 58.7 GB | 60.2 GB | 57.7 GB | +37.3 GB |
| Q5_K_M | 50.7 GB | 52.2 GB | 49.7 GB | +45.3 GB |
| Q4_K_M | 43.4 GB | 44.9 GB | 42.4 GB | +52.6 GB |
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Top-ranked open-source models that fit in 96.0GB.
FAQ
Can the AMD Ryzen AI Max+ 395 (128GB) run Mistral Medium 3.5?
Yes. The AMD Ryzen AI Max+ 395 (128GB)'s 96.0GB of unified memory is enough to run Mistral Medium 3.5 at Q8_0 quantization (75.4GB required).
What's the best quantization to use?
Q8_0 is the highest-precision quantization that fits in your 96.0GB. It uses about 75.4GB of memory and 76.9GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.