Can I Run Mistral Medium 3.5 on a AMD Ryzen AI Max+ 395 (64GB)?
Runs at Q4_K_M — good quality with reasonable headroom.
1 quant fit your 48.0GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| Q4_K_MBEST | 43.4 GB | 44.9 GB | 42.4 GB | +4.6 GB |
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FAQ
Can the AMD Ryzen AI Max+ 395 (64GB) run Mistral Medium 3.5?
Yes. The AMD Ryzen AI Max+ 395 (64GB)'s 48.0GB of unified memory is enough to run Mistral Medium 3.5 at Q4_K_M quantization (43.4GB required).
What's the best quantization to use?
Q4_K_M is the highest-precision quantization that fits in your 48.0GB. It uses about 43.4GB of memory and 44.9GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.