Can I Run NVIDIA Nemotron 3 Super on a AMD Instinct MI325X?
Runs at Q5_K_M — good quality with reasonable headroom.
2 quantizations fit your 256GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| Q5_K_MBEST | 242.4 GB | 243.9 GB | 241.4 GB | +13.6 GB |
| Q4_K_M | 207.1 GB | 208.6 GB | 206.1 GB | +48.9 GB |
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Top-ranked open-source models that fit in 256GB.
FAQ
Can the AMD Instinct MI325X run NVIDIA Nemotron 3 Super?
Yes. The AMD Instinct MI325X's 256GB of VRAM is enough to run NVIDIA Nemotron 3 Super at Q5_K_M quantization (242.4GB required).
What's the best quantization to use?
Q5_K_M is the highest-precision quantization that fits in your 256GB. It uses about 242.4GB of memory and 243.9GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.