Can I Run Qwen 3 Next 80B A3B on a AMD Instinct MI300X?
Runs at full precision (fp16). Zero quality loss.
5 quantizations fit your 192GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| fp16BEST | 161.0 GB | 162.5 GB | 160.0 GB | +31.0 GB |
| Q8_0 | 86.0 GB | 87.5 GB | 85.0 GB | +106.0 GB |
| Q6_K | 66.9 GB | 68.4 GB | 65.9 GB | +125.1 GB |
| Q5_K_M | 57.8 GB | 59.3 GB | 56.8 GB | +134.2 GB |
| Q4_K_M | 49.5 GB | 51.0 GB | 48.5 GB | +142.5 GB |
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FAQ
Can the AMD Instinct MI300X run Qwen 3 Next 80B A3B?
Yes. The AMD Instinct MI300X's 192GB of VRAM is enough to run Qwen 3 Next 80B A3B at fp16 quantization (161.0GB required).
What's the best quantization to use?
fp16 is the highest-precision quantization that fits in your 192GB. It uses about 161.0GB of memory and 162.5GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.