Can I Run Qwen3 4B Thinking 2507 on a AMD Ryzen AI Max+ 395 (64GB)?
Runs at full precision (fp16). Zero quality loss.
13 quantizations fit your 48.0GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| fp16BEST | 9.0 GB | 10.5 GB | 8.1 GB | +39.0 GB |
| Q8_0 | 5.3 GB | 6.8 GB | 4.3 GB | +42.8 GB |
| Q6_K | 4.3 GB | 5.8 GB | 3.3 GB | +43.7 GB |
| Q5_K_M | 3.8 GB | 5.3 GB | 2.9 GB | +44.2 GB |
| Q5_K_S | 3.8 GB | 5.3 GB | 2.8 GB | +44.2 GB |
| Q4_1 | 3.5 GB | 5.0 GB | 2.6 GB | +44.5 GB |
| Q4_K_M | 3.4 GB | 4.9 GB | 2.5 GB | +44.6 GB |
| Q4_K_S | 3.3 GB | 4.8 GB | 2.4 GB | +44.7 GB |
| Q4_0 | 3.3 GB | 4.8 GB | 2.4 GB | +44.8 GB |
| Q3_K_L | 2.8 GB | 4.3 GB | 2.2 GB | +45.2 GB |
| Q3_K_M | 2.7 GB | 4.2 GB | 2.1 GB | +45.3 GB |
| Q3_K_S | 2.5 GB | 4.0 GB | 1.9 GB | +45.5 GB |
| Q2_K | 2.3 GB | 3.8 GB | 1.7 GB | +45.7 GB |
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Top-ranked open-source models that fit in 48.0GB.
FAQ
Can the AMD Ryzen AI Max+ 395 (64GB) run Qwen3 4B Thinking 2507?
Yes. The AMD Ryzen AI Max+ 395 (64GB)'s 48.0GB of unified memory is enough to run Qwen3 4B Thinking 2507 at fp16 quantization (9.0GB required).
What's the best quantization to use?
fp16 is the highest-precision quantization that fits in your 48.0GB. It uses about 9.0GB of memory and 10.5GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.