Can I Run / Qwen 3.5 9B / on AMD Instinct MI250X

Can I Run Qwen 3.5 9B on a AMD Instinct MI250X?

Yes

Runs at full precision (f32). Zero quality loss.

Model size
9.7B
GPU memory
128GB
Smallest quant
Q3_K_S
Best fit
f32

12 quantizations fit your 128GB

QuantMin VRAMRecommendedFile sizeHeadroom
f32BEST39.8 GB41.3 GB1.8 GB+88.2 GB
fp1620.4 GB21.9 GB0.9 GB+107.6 GB
Q8_011.3 GB12.8 GB9.5 GB+116.7 GB
Q6_K9.0 GB10.5 GB7.5 GB+119.0 GB
Q5_K_M7.9 GB9.4 GB6.6 GB+120.1 GB
Q5_K_S7.7 GB9.2 GB6.4 GB+120.3 GB
Q4_17.1 GB8.6 GB5.8 GB+120.9 GB
Q4_K_M6.9 GB8.4 GB5.7 GB+121.1 GB
Q4_K_S6.5 GB8.1 GB5.4 GB+121.5 GB
Q4_06.5 GB8.0 GB5.4 GB+121.5 GB
Q3_K_M5.1 GB6.6 GB4.7 GB+122.9 GB
Q3_K_S4.7 GB6.2 GB4.3 GB+123.3 GB

Try it in the cloud first

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Full model details
Qwen 3.5 9B

All quant variants, benchmark scores, and use-case tags.

Best models for this GPU
AMD Instinct MI250X

Top-ranked open-source models that fit in 128GB.

FAQ

Can the AMD Instinct MI250X run Qwen 3.5 9B?

Yes. The AMD Instinct MI250X's 128GB of VRAM is enough to run Qwen 3.5 9B at f32 quantization (39.8GB required).

What's the best quantization to use?

f32 is the highest-precision quantization that fits in your 128GB. It uses about 39.8GB of memory and 41.3GB recommended for comfortable inference.

What if I need more headroom for context length?

KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.