Can I Run Qwen 3.6 35B A3B on a AMD Instinct MI250X?
Runs at full precision (fp16). Zero quality loss.
5 quantizations fit your 128GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| fp16BEST | 71.0 GB | 72.5 GB | 70.0 GB | +57.0 GB |
| Q8_0 | 38.2 GB | 39.7 GB | 37.2 GB | +89.8 GB |
| Q6_K | 29.8 GB | 31.3 GB | 28.8 GB | +98.2 GB |
| Q5_K_M | 25.9 GB | 27.4 GB | 24.9 GB | +102.2 GB |
| Q4_K_M | 22.2 GB | 23.7 GB | 21.2 GB | +105.8 GB |
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FAQ
Can the AMD Instinct MI250X run Qwen 3.6 35B A3B?
Yes. The AMD Instinct MI250X's 128GB of VRAM is enough to run Qwen 3.6 35B A3B at fp16 quantization (71.0GB required).
What's the best quantization to use?
fp16 is the highest-precision quantization that fits in your 128GB. It uses about 71.0GB of memory and 72.5GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.