Can I Run Seed OSS 36B Instruct on a AMD Instinct MI250X?
Runs at Q8_0 — near-lossless quality.
3 quantizations fit your 128GB
| Quant | Min VRAM | Recommended | File size | Headroom |
|---|---|---|---|---|
| Q8_0BEST | 39.5 GB | 41.0 GB | 38.4 GB | +88.5 GB |
| Q6_K | 30.8 GB | 32.3 GB | 29.7 GB | +97.2 GB |
| Q4_K_M | 22.9 GB | 24.4 GB | 21.8 GB | +105.0 GB |
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Top-ranked open-source models that fit in 128GB.
FAQ
Can the AMD Instinct MI250X run Seed OSS 36B Instruct?
Yes. The AMD Instinct MI250X's 128GB of VRAM is enough to run Seed OSS 36B Instruct at Q8_0 quantization (39.5GB required).
What's the best quantization to use?
Q8_0 is the highest-precision quantization that fits in your 128GB. It uses about 39.5GB of memory and 41.0GB recommended for comfortable inference.
What if I need more headroom for context length?
KV cache memory grows with context length. The numbers above assume a baseline 2K-4K context. For long-context use (32K+), add another 2-6GB depending on the model architecture.